PLACE pineapple juice and fruit spread in medium microwave-safe bowl. Microwave on HIGH 1 minute. Whisk until fruit spread is dissolved. Stir in lime juice.
FILL 4 (16-oz.) tall glasses with ice. Divide grape mixture evenly into each glass.
POUR ginger ale into each glass until full. Stir until blended. Serve immediately with lime wedges, if desired.